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Organ System Integration

Renal & Urinary System Complete Content Map

Integrated coverage of embryology, anatomy, histology, physiology, pathology, and pharmacology. Each module includes core topics, high‑yield subtopics, and clinical correlations for Step 1 mastery.

6
Core domains
70+
Core subtopics
60+
Clinical correlations
💧 Renal & Urinary Curriculum
Mapped to USMLE Step 1 content outline. Each block below links to a dedicated module with full hierarchical breakdown — core topics, high‑yield details, and clinical correlations.
6.1

Embryology

Kidney development (pronephros, mesonephros, metanephros), ureteric bud, cloaca, congenital anomalies (horseshoe kidney, duplex collecting system, posterior urethral valves).

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6.2

Gross Anatomy

Kidney position and relations, ureter, bladder, urethra, renal vasculature, retroperitoneal structures.

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6.3

Histology

Nephron structure (glomerulus, tubules, collecting duct), juxtaglomerular apparatus, urothelium.

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6.4

Physiology

GFR, tubular function, countercurrent system, RAAS, ADH, aldosterone, acid‑base handling, potassium homeostasis.

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6.5

Pathology

Glomerular diseases (nephrotic/nephritic syndromes), tubulointerstitial diseases, cystic diseases, urinary tract obstruction, nephrolithiasis, renal cell carcinoma, bladder cancer, acute and chronic kidney disease.

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6.6

Pharmacology

Diuretics, ACE inhibitors/ARBs, drugs affecting uric acid, BPH drugs, overactive bladder medications.

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